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About ICGC

About ICGC

The ARGO Vision

We know each cancer is different, yet we treat them much the same. A major challenge is that we don’t have the information to know ahead of time which treatments will work and which won't. 

The ARGO project is a new phase of the International Cancer Genome Consortium. Launched in 2019 after 10 successful years of the ICGC mapping genomic alterations that characterise over 50 cancer types.  The time has now come to translate this knowledge to improve outcomes for people affected by cancer.

Mission

ICGC ARGO will uniformly analyze specimens from 100,000 cancer patients with high quality clinical data to address outstanding questions that are vital to our quest to defeat cancer. 

Over the next ten years ICGC ARGO aims to deliver a million patient-years of precision oncology knowledge to the world, by making data available to the entire research community in a rapid and responsible way, to accelerate research into the causes and control of cancer. 

Read more about our goals 


Our History

The original initiative (known as the ICGC 25k Project) was to define the genomes of 25,000 primary untreated cancers which to date has produced >20,000 tumour genomes for 26 cancer types. Learn more about the 25k Initiative in the 2010 Marker Paper.

ICGC 25k was the first step to broadly and comprehensively map the structural aberrations of genomes and begin to understand the molecular basis of cancer. Data generated through the ICGC has transformed research strategies in academia and industry alike, with hundreds of seminal works published directly using ICGC data, with landmark articles in the world’s elite scientific journals. No therapeutic is developed today without, in some way, applying the knowledge that ICGC has provided the world.


The second ICGC initiative, the Pan-Cancer Analysis of Whole Genomes (PCAWG) study commenced in 2013 as an international collaboration to identify common patterns of mutation in more than 2,600 cancer whole genomes from the International Cancer Genome Consortium. The Pan-Cancer Analysis of Whole Genomes project published a suite of 23 papers in Nature and affiliated journals in February 2020.


In 2015, in response to the realization of the potential of genomics in healthcare, released a position “white paper” on the evolution of ICGC move directly to impacting on human health. Emanating from the ICGC for Medicine (ICGCmed) outlined the aim to Accelerate Research in Genomic Oncology (ICGC ARGO).


Read the whitepaper

Since launching in 2019, ARGO has grown to 24 member programs across 13 countries, with 14 data releases to date.


Multiple mechanisms and categories of membership to provide opportunities to contribute to ICGC ARGO have been developed. Please contact us admin@icgc-argo.org if you would like to discuss how you or your institution can participate

Download the BROCHURE




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